Seneca presents a profound choice that faces every human being: we can cooperate with life's inevitable changes and challenges, moving forward with dignity and grace, or resist them and be dragged along unwillingly through suffering and struggle. The destination often remains the same - the course of events will unfold as they must - but our experience of the journey depends entirely on our attitude. Those who align themselves with fate become partners in their own destiny, finding meaning and purpose even in difficulty. Those who resist are pulled along against their will, fighting uselessly against forces beyond their control. Wisdom lies in choosing willing participation over futile resistance.